Linfoma difuso de célulasB grandes primario de cérvix. A propósito de un caso / Primary diffuse large Bcell lymphoma of the cervix: Clinical case

Introducción: La afectación primaria del tracto genital femenino por linfoma no Hodgkin es muy poco frecuente, por lo que no existe un consenso sobre el tratamiento, y por ello presentamos este caso clínico y el tratamiento realizado, así como el pronóstico de nuestra paciente. Hallazgos clínicos: La paciente presentada es una mujer de 72años que consulta por hemorragia vaginal. Diagnóstico Se diagnostica de linfoma no Hodgkin extranodal primario de cérvix de inmunofenotipoB de alto grado citológico y elevado índice proliferativo. Intervenciones terapéuticas y resultados: El tratamiento de elección fue únicamente quimioterápico. Esta paciente ha presentado una supervivencia libre de enfermedad de 5años. Actualmente se encuentra en seguimiento mediante la realización de controles analíticos anuales. Conclusión: Los síntomas de este tipo de tumor son altamente inespecíficos y la citología es frecuentemente negativa, por lo que es necesario recurrir a la biopsia. La inmunohistoquímica resulta fundamental tanto para el diagnóstico como para el pronóstico. Existen múltiples técnicas de imagen empleadas tanto para estudio de extensión como para seguimiento, destacando el papel del FDG-PET. Actualmente parece que el tratamiento más recomendable es la pauta quimioterápica R-CHOP seguida de radioterapia. El pronóstico en general es bueno, con hasta un 80% de supervivencia a los 5años.(AU)

Introduction: Primary involvement of the female genital tract by non-Hodgkin lymphoma is very rare, so there is no consensus on treatment, and for this reason we present this clinical case and the treatment performed, as well as the prognosis of our patient. Clinical findings: The patient presented is a 72-year-old woman who consulted for vaginal bleeding. Diagnosis: Primary extranodal non-Hodgkin lymphoma of the cervix with immunophenotypeB of high cytological grade and high proliferative index was diagnosed. Therapeutic interventions and results: The treatment of choice was chemotherapy only. This patient has presented a disease-free survival of 5years. It is currently being monitored by carrying out annual analytical controls. Conclusion: The symptoms of this type of tumor are highly non-specific, as well as cytology is frequently negative, which is why it is necessary to resort to biopsy. Immunohistochemistry is essential for both diagnosis and prognosis. There are multiple imaging techniques used for both extension study and follow-up, highlighting the role of FDG-PET. It currently seems that the most recommendable treatment is the R-CHOP chemotherapy regimen followed by radiotherapy.The prognosis is generally good, with up to 80% survival at 5years.(AU)

Acretismo placentario focal tratado mediante embolización de arterias uterinas / Focal placenta accreta treated by uterine artery embolisation

El acretismo placentario es causa de hemorragia posparto y es una entidad que incrementa considerablemente la morbimortalidad materna. El diagnóstico anteparto es difícil. La embolización selectiva del vaso nutricio es una técnica conservadora que permite preservar el útero, y por lo tanto conservar la fertilidad. Presentamos el caso de una mujer con hemorragia puerperal, en el que se planteó el diagnóstico diferencial entre acretismo focal y malformación arterio-venosa uterina, que se trató exitosamente mediante embolización de arterias uterinas y posterior legrado, preservando fertilidad y consiguiendo nuevo embarazo posteriormente. Se evalúa la importancia de la interpretación de las imágenes para el diagnóstico, y la adaptación individual de los métodos terapéuticos y el manejo multidisciplinar

Placenta accreta can cause postpartum bleeding and has high maternal morbidity and mortality. Prenatal diagnosis is difficult. Selective embolisation of the uterine artery is a conservative technique that preserves the uterus and fertility. We present the case of a woman with puerperal bleeding, with a postulated differential diagnosis of focal placenta accreta and uterine arteriovenous malformation. Uterine artery embolisation and curettage successfully preserved fertility and the patient subsequently conceived again. We discuss the importance of image interpretation for correct diagnosis, the personalised adaptation of therapeutic methods and a multidisciplinary approach

Penfigoide gestacional / Pemphigoid gestationis

El penfigoide gestacional (PG) o herpes gestationis es una rara enfermedad cutánea autoinmune, que generalmente aparece en el segundo y tercer trimestre, y durante el puerperio, y que puede afectar al curso de la gestación y producir afectación neonatal. Presentamos el caso de una secundigesta con gestación gemelar y pénfigo gestacional. Se describe el proceso de diagnóstico, tratamiento y evolución

The pemphigoid gestationis or herpes gestationis is a rare autoimmune skin disease that occurs during the second or third trimester of pregnancy or in the immediate postpartum and which may affect the course of the pregnancy and cause neonatal pemphigoid gestationis. We present the case of a 40-year-old secudigravida with a twin pregnancy and pemphigoid gestationis. We describe the diagnostic process, treatment, and outcome

Fetal intracranial immature teratoma: presentation of a case and a systematic review of the literature.

OBJECTIVES: To describe a case diagnosed with intracranial teratoma in week 32 of gestation, as well as review of the literature in order to discern the appropriate treatment method and general prognosis of this anomaly. METHODS: A literature search was performed on the prenatal diagnosis of congenital intracranial teratomas in MEDLINE, EMBASE, Cochrane library data bases. Evaluated in this review are parameters such as time of prenatal diagnosis, associated pathology, size of tumors, method of terminating pregnancy, perinatal outcome and histological study of the tumor. RESULTS: A total of 49 cases were found, of which 12 were finished gestation, 28 cesarean section was performed and only nine had vaginal delivery. All died in the neonatal period except in three cases with intrauterine death after diagnosis. CONCLUSION: As the incidence of intracranial immature teratomas is very low and the prognosis is poor, their prenatal diagnosis and obstetric management present a great challenge for the planning of a follow-up and treatment of the disease in accordance with the preferences of the parents.